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Creatine isn't just for the gym

Creatine is familiar in sport. Researchers are also studying its role in memory and mental performance.

For years, creatine was known as a bodybuilding supplement. Researchers are now looking closely at what it does for the brain, too.

The brain has high energy needs. Creatine is involved in how cells recycle energy, which has prompted researchers to study its role beyond exercise.

Creatine is involved in recycling adenosine triphosphate (ATP), a source of cellular energy. Studies have explored changes in brain creatine stores after supplementation, but responses vary and do not guarantee a mental-performance benefit.

Early research suggests creatine supplementation may help support memory and mental performance, including during short periods of sleep loss. The evidence is still developing, and benefits are not guaranteed.

Works cited

  1. Candow, D. G., Forbes, S. C., Ostojic, S. M., Prokopidis, K., Stock, M. S., Harmon, K. K., & Faulkner, P. (2023). "Heads Up" for Creatine Supplementation and its Potential Applications for Brain Health and Function. Sports Medicine, 53, 49-65. https://doi.org/10.1007/s40279-023-01870-9
  2. Roschel, H., Gualano, B., Ostojic, S. M., & Rawson, E. S. (2021). Creatine Supplementation and Brain Health. Nutrients, 13(2), 586. https://doi.org/10.3390/nu13020586